Kimberly directs a laboratory in the Green Center for Systems Biology and holds a secondary appointment in Biophysics at UT Southwestern, where she is searching for statistical rules that govern the assembly of functioning cellular systems. By conducting comparative analyses of genomic data from diverse species, she hopes to distill general principles that describe how cellular systems are built and evolve. In particular, she would like to relate systematic patterns of genetic variation to changes in biological behavior. She tests the predictions of these statistical models by conducting high-throughput genetics and forward evolution experiments.
The impact of this work lies in our ability to understand the information content of the genome. Our capacity to predict, control, and engineer cellular behavior depends critically on a quantitative model describing the importance and interaction of individual genes. Kim hopes to arrive at such a model through the careful study of large-scale genomic data.
Kim is a 2016 Scialog fellow. She earned her PhD from the University of California, Berkeley, and trained as a postdoctoral fellow at both the Scripps Research Institute, and UT Southwestern.
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University of Texas Southwestern Medical Center, Green Center for Systems Biology