Biographical Sketch Example
VICKI L. CHANDLER
U.C. Berkeley, CA, Cum Laude & major honors, B.A. in Biochemistry 1978; Undergraduate Research with Professor Randy Schekman, Dept. of Biochemistry
Cold Spring Harbor Laboratory, CSH, NY, Summer Undergraduate Research Program 1977; with Dr. Ray Gestland
U.C. San Francisco, CA, Ph.D., Biochemistry; Dept. of Biochemistry & Biophysics, 1983; with Professor Keith Yamamoto
Stanford University, Stanford, CA, Postdoctoral Fellow, Dept. of Biological Sciences, 1983-85; with Professor Virginia Walbot
2009-present Chief Program Officer-Science, Gordon and Betty Moore Foundation
2006-present Member, Arizona Cancer Center, University of Arizona, Tucson
2005-present Weiler Endowed Chair in Agriculture and Life Sciences, Univ. Arizona
2004-2009 Director, BIO5 Institute, University of Arizona, Tucson (Co-Director 2002-2004)
2003-present Regents' Professor, University of Arizona, Tucson
1997-present Professor, Dept. of Plant Sciences, University of Arizona, Tucson
1998-present Professor, Molecular Cellular Biology Dept., Univ. of Arizona, Tucson
1998-present Member, Interdisciplinary Program in Genetics, Univ. of Arizona, Tucson
1985-1997 Assistant, Associate and Full Professor of Biology; Member, Institute of Molecular Biology, University of Oregon, Eugene, OR
i) Five Publications Most Closely Related to the Submitted Idea
Arteaga-Vazquez, M., , L., F.A.,, R.,, K., P.J.,, B.C.andRNA-mediatedtrans-communication can establish paramutation at theb1locus in maize. PNAS 107:12986-12991.
Brzeska, K., Brzeski, J., Smith, J. and V.L. Chandler. 2010. Transgenic expression of CBBP, a CXC domain protein, establishes paramutation in maize. PNAS 107: 5516-5521.
Sidorenko, L., J.E. Dorweiler, A.M. Cigan, M. Arteaga-Vazquez, M. Vyas, J. Kermicle, D. Jurcin, J. Brzeski, Y. Cai, and V. L. Chandler. 2009. A dominant mutation in Mediator of paramutation 2, one of three second largest subunits of plant-specific RNA Polymerase, disrupts multiple silencing processes. PLoS Genetics 5:1-18.
Alleman, M, L. Sidorenko, K. McGinnis, V. Seshadri, J.E. Dorweiler, J. White, K. Sikkink, and V.L. Chandler. 2006. An RNA-dependent RNA polymerase is required for paramutation in maize. Nature 442:295-98.
Stam, M, C. Belele, J.E. Dorweiler, and V.L. Chandler. 2002. Differential chromatin structure within a tandem array 100 kb upstream of the maize b1 locus is associated with paramutation. Genes Dev 16:1906-18.
ii) Five Other Publications
Chandler, V. 2007. Paramutation: From Maize to Mice. Cell 128(4), 641-645.
McGinnis, K.M., C. Springer, Y. Lin, C.C. Carey, and V.L. Chandler. 2006. Transcriptionally silenced transgenes in maize are activated by 3 mutations defective in paramutation. Genetics 173:1637-47.
Lisch, D., C.C. Carey, J.E. Dorweiler, and V.L. Chandler. 2002. A mutation that prevents paramutation in maize also reverses Mutator transposon methylation and silencing. PNAS 99:6130-35.
Goff, S.A., K.C. Cone, and V.L. Chandler. 1992. Functional analysis of the transcriptional activator encoded by the maize B gene:evidence for a direct functional interaction between two classes of regulatory proteins. Genes Dev 6:864-75.
Goff, S.A., Klein, T.M., Roth, B.A., Fromm, M.E., Cone, K.C., Radicella, J.P. and V.L. Chandler. 1990. Transactivation of anthocyanin biosynthetic genes following transfer of B regulatory genes into maize tissues. EMBO J. 9: 2517-2522.
Selected Honors and Recognition
2005: Recipient, NIH Director's Pioneer Award - Fellow AAAS
2002: Elected to National Academy of Sciences, USA.
1991: NSF Faculty Awards for Women Scientists & Engineers
1988: Searle Scholar
1985: Presidential Young Investigator Award
1983-1985: NSF Plant Biology Postdoctoral Fellowship
Total graduate students trained: 16; total postdoctoral trainees: 23; total undergraduate trainees: 104.
Community Resource Projects